Something I just learned about from the news (interestingly enough, within the same week, the news has talked about it, as has a radio station, and my school newspaper):
Binaural beats are being used to replicate sensations of being "high."
The company I-Doser
offers tracks called "doses" which are named after illegal and legal drugs. They claim that they can replicate the experience of actually using such drugs.
I'm highly skeptical, and don't think it's possible to really replicate something like heroin or marijuana by using sounds, but countless testimony from users of i-doser say that the effects can be very dramatic (spacing out, extreme relaxation, strange muscle contractions, audio-visual hallucinations, etc).
I'm tempted to try it, but as mentioned, I'm highly skeptical. The software download comes with two free "doses" but the rest all cost money. Even if it does have some merit, I don't think I'd ever spend money on it.