dennisfrancisblewett Posted December 30, 2021 Report Posted December 30, 2021 (edited) So, in about the past week or two, I've been reflecting on how something like the bubonic plague might pop-up with SARS-CoV-2 if fleas are able to host and/or transmit the disease. Presumptively, mice are able to host and transmit SARS-CoV-2 (1). Thoughts? (1) "Infection of wild-type mice by SARS-CoV-2 B.1.351 variant indicates a possible novel cross-species transmission route - PubMed." <https://www.nature.com/articles/s41392-021-00848-1> UPDATE: I just found this: Quote In relation to COVID-19, these findings raise several questions that may be relevant for the identification of the possible SARS-CoV-2 animal hosts and transmission routes. Recent results support that infections in domestic cats likely come from the human-to-pet transmission of the SARS-CoV-2 [17]. Furthermore, current evidence suggests that pets are probably dead-end-hosts with small risk of transmission to humans [10]. Nevertheless, our results suggested that arthropod ectoparasite vectors of cats such as Ctenocephalides spp. fleas may act as biological and/or mechanical vectors of SARS-CoV. Although preliminary, these results indicate the possibility of ectoparasites acting as reservoirs and vectors of SARS-CoV and related beta-coronaviruses although with little disease risk due to systemic transmission route, low viremia when compared to vector-borne flaviviruses, virus attenuation or other unknown factors. Future studies should further explore the presence of SARS-CoV-2 in fleas collected from cats in regions with high COVID-19 prevalence. Although the results support conservation of ACE proteins in arthropod vectors such as fleas and ticks, their functional interaction with SARS-CoV-2 and other SARS-CoV needs to be investigated. Therefore, experimental infestation of SARS-CoV-2-infected cats with cat fleas is required to prove the possible transmission of the coronavirus by arthropod vectors. source: Coronavirus in cat flea: findings and questions regarding COVID-19 | Parasites & Vectors | Full Text (biomedcentral.com) Well, if the spike protein for SARS-CoV is molecularly the same as the spike protein for SARS-CoV-2 (whereby it allows docking just like for SARS-CoV), then it may be deduced the answer is "yes." Such presumes that a cat flea could just as well end up on a mouse. Edited December 30, 2021 by dennisfrancisblewett Quote
OceanBreeze Posted December 30, 2021 Report Posted December 30, 2021 It is certainly possible that Sars-Covid can be carried and transmitted by animals such as rats. There have been studies confirming this. (Scroll down to Page 177) However, a comparison with the Bubonic Plague seems to be quite a stretch. We now understand viruses and have both vaccines as well as effective treatments for those who are infected. Also, despite the alarming numbers of deaths being reported, most of those deaths have occurred in people with other underlying Comorbidities, such as heart disease, obesity, diabetes and many others, plus most of the deaths have occurred in elderly people. Young people, who are otherwise healthy, do not usually suffer from severe illness from Covid. In my opinion, it is ridiculous to vaccinate young children and force them to wear masks. In fact, it is now generally accepted that the paper and cloth masks worn by most people have no effectiveness at all against covid infection. Young people often end up with masks that are clogged with mucous, causing breathing problems, as well as bacterial infections. Our entire approach to dealing with this disease needs to be re-evaluated and changed. Unfortunately, unelected public servants such as Dr Fauci, who has been wrong so many times, but is entrenched in his position, will continue to lead us astray until he is finally removed. Short answer: No, there will not be anything like the Bubonic Plague, but since animals, such as rats and even house pets, can carry this disease, it will be with us for a long time, perhaps permanently. Quote
Vmedvil2 Posted December 31, 2021 Report Posted December 31, 2021 7 hours ago, dennisfrancisblewett said: So, in about the past week or two, I've been reflecting on how something like the bubonic plague might pop-up with SARS-CoV-2 if fleas are able to host and/or transmit the disease. Presumptively, mice are able to host and transmit SARS-CoV-2 (1). Thoughts? (1) "Infection of wild-type mice by SARS-CoV-2 B.1.351 variant indicates a possible novel cross-species transmission route - PubMed." <https://www.nature.com/articles/s41392-021-00848-1> UPDATE: I just found this: source: Coronavirus in cat flea: findings and questions regarding COVID-19 | Parasites & Vectors | Full Text (biomedcentral.com) Well, if the spike protein for SARS-CoV is molecularly the same as the spike protein for SARS-CoV-2 (whereby it allows docking just like for SARS-CoV), then it may be deduced the answer is "yes." Such presumes that a cat flea could just as well end up on a mouse. On the subject of is COVID going to be the bubonic plague, the answer is "No" the reason it isn't because they didn't have a cure or vaccination for the bubonic plague back in the medieval times which the bubonic plague even in current times without antibiotic treatments will still kill you and is highly hazardous to health without antibiotics, but back in the medieval times there was nothing they could do about bacterial diseases because antibiotics had not been discovered yet, that situation just isn't the case with this viral pandemic we call COVID there is a vaccination that prevents severe symptoms such as "Death" most of the time just as antibiotics for bubonic plague. The situation is vastly different than 700 years ago because of technologies to prevent disease, we "Cured" COVID within a year of the initial outbreak, the bubonic plague was never cured until antibiotics were discovered in 1928, so for 600 years if you got bubonic plague you were in a bad spot which makes the situation vastly different. Once COVID is added as a vaccination that is mandatory for children like MMR vaccine or various other vaccines this disease will simply cease to exist besides for the very few unvaccinated people that weren't given it as a child. While the human psychology hasn't changed in 700 years our technology has changed quite a bit in 700 years thus there will be a different outcome for this disease then the years of the bubonic plague 700 years ago. Link = https://my.clevelandclinic.org/health/diseases/21590-bubonic-plague Link = https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/covid-19-vaccines 3 hours ago, OceanBreeze said: It is certainly possible that Sars-Covid can be carried and transmitted by animals such as rats. There have been studies confirming this. (Scroll down to Page 177) However, a comparison with the Bubonic Plague seems to be quite a stretch. We now understand viruses and have both vaccines as well as effective treatments for those who are infected. Also, despite the alarming numbers of deaths being reported, most of those deaths have occurred in people with other underlying Comorbidities, such as heart disease, obesity, diabetes and many others, plus most of the deaths have occurred in elderly people. Young people, who are otherwise healthy, do not usually suffer from severe illness from Covid. In my opinion, it is ridiculous to vaccinate young children and force them to wear masks. In fact, it is now generally accepted that the paper and cloth masks worn by most people have no effectiveness at all against covid infection. Young people often end up with masks that are clogged with mucous, causing breathing problems, as well as bacterial infections. Our entire approach to dealing with this disease needs to be re-evaluated and changed. Unfortunately, unelected public servants such as Dr Fauci, who has been wrong so many times, but is entrenched in his position, will continue to lead us astray until he is finally removed. Short answer: No, there will not be anything like the Bubonic Plague, but since animals, such as rats and even house pets, can carry this disease, it will be with us for a long time, perhaps permanently. Well, in my state if you are fully vaccinated you don't have to wear a mask, I always thought the masks were kinda stupid too. Really what people need to be wearing is a bio-hazard suit that would make it impossible to get infected by any airborne disease especially if it was a Class A encapsulated bio-hazard suit. Masks don't really offer much protection in the grand scheme of things, if you think a little piece of cloth is going to magically deflect virus particles that are airborne then you are sadly mistaken. Quote
dennisfrancisblewett Posted December 31, 2021 Author Report Posted December 31, 2021 (edited) Well, if the virus attacks ACE2 and such is in epithelial tissue, then a flea bite with virility would infect a person with SARS-CoV-2. See also: "Mechanisms of SARS-CoV-2 Transmission and Pathogenesis." Harrison, et. al. Dec. 2020. Trends in Immunology. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556779/> Edited January 7, 2022 by dennisfrancisblewett Provided context to link Quote
Autodidactocrat Posted December 31, 2021 Report Posted December 31, 2021 "Dodn't play well with others" ✓ https://youtu.be/CsIFyTkvLCk Quote
Vmedvil2 Posted January 1, 2022 Report Posted January 1, 2022 (edited) 16 hours ago, dennisfrancisblewett said: Well, if the virus attacks ACE2 and such is in epithelial tissue, then a flea bite with virility would infect a person with SARS-CoV-2. See also: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556779/ I am not denying the zoonotic properties of COVID, this coronavirus family of viruses can be found in bats along with various other lifeforms and I think a researcher that was bitten by some mouse was even infected in a laboratory setting, I think you are 100% correct that various animals could be carriers of the COVID virus. Link = https://www.theguardian.com/world/2021/dec/10/mouse-bite-infected-taiwan-lab-woker-covid Rabies has highly zoonotic properties too, COVID would not be the only disease that can be spread by animals, but to say COVID or Rabies is going to be exactly like Bubonic plague is a vast generalization. As I said previously the bubonic plague happened a long time ago and things have changed quite a bit in that time. All Zoonotic diseases are going to be "Something" like the bubonic plague in the respect that they can be spread by animals but in other respects they are nothing alike for instance COVID is a virus and not a bacteria like the bubonic plague. Edited January 1, 2022 by VictorMedvil Quote
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