Diamporphine hydrochloride and derivatives

[joho]

Will diamorphine hydrochloride react with sodium hydroxide to give diamorphine free base? Yes or No.

 

Not a drug dealer! Its an exam question!:)

[Mercedes Benzene]

Nope. I'm pretty sure it would not.

:)

[Mercedes Benzene]

ACUTALLY:

I want to change my above answer. :)

My mistake.... I am fairly certain that it WOULD produce the free base form by reacting it with sodium hydroxide.

Sorry.....:(

[joho]

ACUTALLY:

I want to change my above answer. :)

My mistake.... I am fairly certain that it WOULD produce the free base form by reacting it with sodium hydroxide.

Sorry.....:)

 

Thanks, but can you give me an idea how? An equation maybe or point me somewhere I can find one?

[UncleAl]

An amine hydrochloride will obviously be neutralized by sodium hydroxide solution. Look at the pKa values. Kinetics of reaction can depend on steric hindrance and electronics, e.g., 2,2,6,6-tetramethylpiperidine and 1,8-bis(dimethylamino)naphthlene.

 

Will NaOH do evil to other parts of your molecule?

[Kayra]

OK UncleAl, now your just making up words.

 

:)

[UncleAl]

OK UncleAl, now your just making up words.;)

http://www.mazepath.com/uncleal/sunshine.jpg

[TheBigDog]

http://www.mazepath.com/uncleal/sunshine.jpg

I am not sure what is more impressive; the flexibility or the depth.

 

Bill

[Kayra]

http://www.mazepath.com/uncleal/sunshine.jpg

 

 

Ooch.

Impressive penetration.

 

Did I mention that they were very GOOD words?

[joho]

An amine hydrochloride will obviously be neutralized by sodium hydroxide solution. Look at the pKa values. Kinetics of reaction can depend on steric hindrance and electronics, e.g., 2,2,6,6-tetramethylpiperidine and 1,8-bis(dimethylamino)naphthlene.

 

Will NaOH do evil to other parts of your molecule?

 

Mmmhhm. Yep. Yep. I see. Thanks. Haven't got a clue what you mean but thanks! Like the pic - hope thats not you!::)

[Kayra]

Mmmhhm. Yep. Yep. I see. Thanks. Haven't got a clue what you mean but thanks! Like the pic - hope thats not you!::hihi:

 

I find that if you re-read old UncleAl's posts about 3-2,000 times they actually start to make sense.

 

At least I see I am not alone.